Rassf Family of Tumor Suppressor Polypeptides
نویسندگان
چکیده
منابع مشابه
RASSF6; the Putative Tumor Suppressor of the RASSF Family.
Humans have 10 genes that belong to the Ras association (RA) domain family (RASSF). Among them, RASSF7 to RASSF10 have the RA domain in the N-terminal region and are called the N-RASSF proteins. In contradistinction to them, RASSF1 to RASSF6 are referred to as the C-RASSF proteins. The C-RASSF proteins have the RA domain in the middle region and the Salvador/RASSF/Hippo domain in the C-terminal...
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1 JG Brown Cancer Center, University of Louisville, 417 CTR Building, 505 S. Hancock Street, Louisville, KY 40202, USA 2Division of Hematology/Oncology, Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, 3-055 Katz Group Centre for Pharmacy and Health Research, 113 Street 87 Avenue, Edmonton, AB, Canada T6G 2E1 3School of Clinical and Experimental Medicine, Coll...
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متن کاملRASSF proteins
What are RASSF proteins? RASSF stands for Ras association domain family. This family represents a group of ten mammalian proteins that contain a Ras association (RA) domain (Figure 1A). The first member of this family was identified as a binding partner of the Ras oncoprotein and was named NORE1 (novel Ras effector 1; now called RASSF5). The hunt for tumor suppressor genes on chromosome 3p21.3,...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2009
ISSN: 0021-9258
DOI: 10.1074/jbc.r800073200